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Why p value inconsistent when using different number of pathway score?
limma
updated 20 minutes ago by
ATpoint
★ 4.0k • written 1 hour ago by
Chris
• 0
15
votes
22
replies
1.7k
views
The difference when using Limma compare between 3 conditions vs 2 conditions
limma
21 days ago • updated 1 hour ago
Chris
• 0
0
votes
0
replies
9
views
I am trying to detect alternative splicing but getting error.
ASpli
2 hours ago
Sebashish
• 0
0
votes
0
replies
10
views
I am trying to detect alternative splicing.
ASpli
2 hours ago
Sebashish
• 0
3
votes
1
reply
1.4k
views
Job:
Post Doctoral position in AI (Deep learning / Machine learning) approaches for Cancer Research, MRC Cancer Unit, University of Cambridge, UK
job
Job
machine learning
deep learning
computational biology
written 6.3 years ago by
Shamith.Samarajiwa
▴ 180
0
votes
2
replies
749
views
Job:
Bioinformatics Laboratory Head in AI or machine learning (WEHI, Australia)
bioconductor
artificialintelligence
JobPosting
machinelearning
written 7 months ago by
Gordon Smyth
50k
0
votes
4
replies
142
views
Differential peaks that were not identified in diffbind were identified in diseq2
DiffBind
DESeq2
ATACSeq
3 days ago • updated 9 hours ago
lonn
• 0
0
votes
1
reply
62
views
Cannabis and KEGGgraph
KEGGREST
GenomicDistributionsData
KEGGgraph
KEGG
updated 15 hours ago by
deeenes
▴ 30 • written 18 hours ago by
fernanda.backsouza
• 0
0
votes
1
reply
58
views
RNAseq:Technical replicates from different batches
technicalReplicates
BatchEffect
limma
RNASeq
updated 16 hours ago by
Gordon Smyth
50k • written 1 day ago by
catv
• 0
1
vote
1
reply
839
views
DMR.Plot shows error "Error in simpleLoess(y, x, w, span, degree = degree, parametric = FALSE, : NA/NaN/Inf in foreign function call (arg 1)"
DMRcate
Gviz
updated 17 hours ago by
russ.bainer
▴ 10 • written 13 months ago by
jose.ramirez1
▴ 10
1
vote
2
replies
200
views
How to retrieve detailed regression results from deseq2
DESeq2
9 days ago • updated 21 hours ago
Weiqian
▴ 10
1
vote
0
replies
112
views
Tutorial:
Installing/switching between versions of R/Rstudio/Bioconductor on personal machine (Linux | Ubuntu)
bioconductor
Install
1 day ago • updated 22 hours ago
BioinfGuru
▴ 30
0
votes
0
replies
30
views
FDR via q-value
qvalue
22 hours ago
John
• 0
0
votes
6
replies
564
views
News:
List of Deprecated Packages for Bioc3.19
Release
Devel
ExperimentData
Software
7 weeks ago • updated 23 hours ago
shepherl
3.8k
0
votes
4
replies
198
views
FilterByExpr low counts with small sample size
edgeR
2 days ago • updated 1 day ago
Jonathan
▴ 10
0
votes
7
replies
358
views
DESeq filtering specific to contrasts
DESeq2
updated 1 day ago by
Michael Love
41k • written 9 weeks ago by
Emma
• 0
5
votes
14
replies
2.2k
views
DESeq2 a lot of genes showing up as differentially expressed that only have 1 sample with any expression
deseq2
updated 1 day ago by
Seyram M.
• 0 • written 4.6 years ago by
hsbio
▴ 10
0
votes
2
replies
222
views
Odd behavior of Rsubread::featureCounts when setting `nonOverlap = 0`
featureCounts
Rsubread
19 days ago • updated 1 day ago
isaac.vock
• 0
0
votes
3
replies
59
views
Error retrieving ensembl gene id using biomaRt...
biomaRt
updated 1 day ago by
James W. MacDonald
65k • written 1 day ago by
bas_work
▴ 30
2
votes
5
replies
673
views
DESeq2 setting significant p-value
DESeq2
updated 1 day ago by
Michael Love
41k • written 5.0 years ago by
Merlin
▴ 10
1
vote
2
replies
78
views
OrgDb for maize
clusterProfiler
OrgDb
biomaRt
Zea_mays
updated 1 day ago by
James W. MacDonald
65k • written 1 day ago by
sansan
• 0
6
votes
10
replies
1.5k
views
Which input file is used for DGEList in EgdeR?
salmon
edgeR
tximport
nf-core
gene_counts
updated 1 day ago by
i.atanasoai
• 0 • written 14 months ago by
mohammedtoufiq91
▴ 10
0
votes
4
replies
205
views
DEG with low counts
DESeq2
updated 1 day ago by
Michael Love
41k • written 5 days ago by
Rajat
• 0
6
votes
5
replies
383
views
Estimating Cell Counts for EPIC V2 array data
FlowSorted.Blood.EPIC
minifi
written 7 weeks ago by
Kim
• 0
0
votes
3
replies
83
views
Finding DEGs by using edgeR
subsettingdata
edgeR
designmatrix
updated 1 day ago by
Gordon Smyth
50k • written 1 day ago by
prity6459
• 0
0
votes
2
replies
59
views
How to make DGEList and design matrix by edgeR package
DGEList
edgeR
1 day ago
prity6459
• 0
0
votes
1
reply
74
views
Log-cpm values from limma
limma
edgeR
RNASeq
updated 1 day ago by
Gordon Smyth
50k • written 2 days ago by
Shaimaa Gamal
• 0
0
votes
2
replies
891
views
Problem for loading Bioconductor package in R
Bioconductor
written 4.2 years ago by
araaaju
• 0
4
votes
8
replies
312
views
Memory errors using read.bismark?
dmrseq
bsseq
updated 1 day ago by
Peter Hickey
▴ 740 • written 9 days ago by
Juan Higareda
• 0
11
votes
5
replies
7.3k
views
Theoretical WGCNA Question
WGCNA
Theory
Scale-Free Topology
updated 1 day ago by
Garrett
• 0 • written 9.1 years ago by
brohawndg
▴ 150
0
votes
4
replies
89
views
FGSEA pre-ranked input in increasing order or decreasing
fgsea
1 day ago
sropri
• 0
1
vote
2
replies
150
views
significant difference of p-values with dream() after updating VariancePartition
variancePartition
2 days ago • updated 1 day ago
Le
• 0
1
vote
2
replies
755
views
How to tell and visualize up/down regulation of pathways from clusterprofiler gsea output
clusterProfiler
RNASeq
updated 1 day ago by
sredemption
• 0 • written 13 months ago by
ruiqi.li
▴ 10
0
votes
0
replies
32
views
Error EPICv2 ChAMP
ChAMPdata
IlluminaHumanMethylationEPICv2anno.20a1.hg38
ChAMP
1 day ago
Mirella Aurora
• 0
0
votes
3
replies
201
views
A ComBat-seq issue: the covariates are confounded
ComBat-seq
sva
updated 1 day ago by
W. Evan Johnson
▴ 850 • written 8 days ago by
schlumbohm
• 0
0
votes
0
replies
49
views
Warning while loading DEP package
DEP
updated 1 day ago by
shepherl
3.8k • written 2 days ago by
Namrata
• 0
0
votes
1
reply
54
views
Different number of exons in reference genome affects DEXSeq analysis
DEXSeq
updated 1 day ago by
Alejandro Reyes
★ 1.9k • written 2 days ago by
Alessia
• 0
0
votes
1
reply
87
views
Adding columns to DEXSeqResults object
DEXSeq
updated 2 days ago by
Alejandro Reyes
★ 1.9k • written 3 days ago by
Clyde
• 0
0
votes
1
reply
59
views
rlog transformation
DESeq2
updated 2 days ago by
Michael Love
41k • written 2 days ago by
ishij9717
• 0
0
votes
1
reply
56
views
ONT long-read RNA sequencing - data analysis options
DESeq2
LongRead
DEXSeq
IsoformSwitchAnalyzeR
RNASeq
updated 2 days ago by
Michael Love
41k • written 2 days ago by
09191919
• 0
0
votes
1
reply
65
views
DESeq2 Error in `.rowNamesDF<-`(x, value = value): Invalid 'row.names' length
DESeq2
updated 2 days ago by
Michael Love
41k • written 3 days ago by
ussarizona
• 0
0
votes
1
reply
82
views
covariate with negative and positive values
DESeq2
updated 2 days ago by
Michael Love
41k • written 3 days ago by
Brynn
• 0
1
vote
2
replies
99
views
Error in champ.load(): The following specified files do not exist
ChAMP
2 days ago
Sherin
• 0
9
votes
12
replies
7.7k
views
Multi factor design edgeR/Deseq2
deseq2
edgeR
rna-seq
updated 2 days ago by
Elizabeth
• 0 • written 8.8 years ago by
gthm
▴ 30
5
votes
9
replies
815
views
Light difference when using coef vs omit a group when compare 3 groups.
limma
9 days ago • updated 2 days ago
Chris
• 0
0
votes
1
reply
58
views
Input Question for deseq.r
RSeqAn
updated 2 days ago by
ATpoint
★ 4.0k • written 2 days ago by
Nina
• 0
0
votes
1
reply
84
views
DESEQ2 output gives multiple groups when only 2 groups are present
DESeq2
updated 2 days ago by
ATpoint
★ 4.0k • written 3 days ago by
quanah.hudson
• 0
3
votes
3
replies
146
views
Reading huge bismark coverage files using bbseq::read.bismark
HDF5Array
BiocGenerics
BiocParallel
Biobase
8 days ago • updated 2 days ago
jacques.imbert
• 0
5
votes
9
replies
1.2k
views
Batch correction and repeated measures
RUVSeq
sva
limma
updated 2 days ago by
Gordon Smyth
50k • written 6 months ago by
Jonathan
▴ 10
0
votes
6
replies
163
views
Methylation Analysis experiment design using Limma
DNAMethylation
limma
methylationArrayAnalysis
updated 2 days ago by
Gordon Smyth
50k • written 3 days ago by
hortense96
• 0
45,554 results • Page
1 of 912
Recent ...
Replies
Answer: Why p value inconsistent when using different number of pathway score?
by
ATpoint
★ 4.0k
Same answer as here: https://support.bioconductor.org/p/9157606/ Adding or removing data (samples, genes, pathways, observations...) chang…
Comment: The difference when using Limma compare between 3 conditions vs 2 conditions
by
Chris
• 0
Thanks Robert!
Comment: The difference when using Limma compare between 3 conditions vs 2 conditions
by
Robert Castelo
★ 3.2k
Hi, your `c2` object storing all the gene sets is probably a `list` object, where element names are the names of the pathways given by MSig…
Comment: Differential peaks that were not identified in diffbind were identified in diseq
by
lonn
• 0
I tried the default normalization and got similar results as above. Perhaps I need to try identifying the difference peak without using dif…
Answer: Cannabis and KEGGgraph
by
deeenes
▴ 30
Hello, I'm a developer of the `OmnipathR` package, and I wrote [a function][1] to access certain KEGG data: library(OmnipathR) cs…
Votes
Comment: The difference when using Limma compare between 3 conditions vs 2 conditions
Installing/switching between versions of R/Rstudio/Bioconductor on personal machine (Linux | Ubuntu)
A: Docker container with bioconductor and devtools
Answer: OrgDb for maize
Comment: significant difference of p-values with dream() after updating VariancePartition
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