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Showing :
apeglm
•
reset
0
Votes
3
Replies
88
Views
Using altHypothesis on apleglm-shrunken log2FoldChanges
apeglm
DESeq2
12 days ago
zefrieira
• 0
0
Votes
1
Reply
64
Views
DESeq2 - shrunken LFC calculation
apeglm
DESeq2
16 days ago
alexandr.gopanenko
• 20
• updated 16 days ago
Michael Love
31k
0
Votes
3
Replies
70
Views
Influence of DEG in ASE analysis within apeglm
apeglm
3 months ago
Vincent.C.
• 0
• updated 3 months ago
Michael Love
31k
1
Vote
1
Reply
69
Views
Exceeding Over-dispersion parameter bbEstDisp
apeglm
bbEstdisp
allele ratio
4 months ago
Vincent.C.
• 0
• updated 4 months ago
Michael Love
31k
5
Votes
10
Replies
138
Views
Allelic imbalance in apeglm
apeglm
Allelic imbalance
concept
5 months ago
Vincent.C.
• 0
• updated 5 months ago
Michael Love
31k
0
Votes
4
Replies
184
Views
Using different LFC shrinkage estimators for spike-in normalised RNA-seq data
deseq2
apeglm
rna-seq
spike-in
5 months ago
nadezda.fursova
• 0
• updated 5 months ago
Michael Love
31k
2
Votes
2
Replies
118
Views
lfcShrink function in DEseq2 and s-values
deseq2
apeglm
5 months ago
josmantorres
• 10
• updated 5 months ago
Michael Love
31k
2
Votes
1
Reply
80
Views
What are the steps to use a complex model of Allelic imbalance through apeglm
apeglm
complex model
ASE
Allelic imbalance
5 months ago
Vincent.C.
• 0
• updated 5 months ago
Michael Love
31k
1
Vote
1
Reply
76
Views
Why s-values instead of p-values with non-default lfcThreshold and apeglm shrinkage in DESeq2
deseq2
apeglm
7 months ago
jabaron.phd
• 0
• updated 7 months ago
Michael Love
31k
0
Votes
4
Replies
176
Views
Reporting S values? Reporting padj values?
deseq2
apeglm
7 months ago
n.tear
• 10
• updated 7 months ago
Michael Love
31k
4
Votes
4
Replies
103
Views
RNA seq analysis using Deseq2 and apeglm lfc shrinkage
deseq2
fdrtool
apeglm
9 months ago
Paul
• 0
• updated 9 months ago
Michael Love
31k
0
Votes
2
Replies
137
Views
Coefficient names for multiple group comparisons to use with lfcShrink & apeglm
deseq2
lfcShrink
apeglm
13 months ago
coulsonr
• 10
• updated 13 months ago
Michael Love
31k
0
Votes
2
Replies
355
Views
lfcShrink in DESeq2
deseq2
apeglm
17 months ago
Meghdad
• 0
• updated 17 months ago
Michael Love
31k
3
Votes
3
Replies
252
Views
Using alternative LFC shrinkage methods for computing p-values in DESeq2
deseq2
apeglm
statistics
20 months ago
zefrieira
• 0
• updated 20 months ago
Michael Love
31k
0
Votes
2
Replies
194
Views
Calculate S/N ratios from apeglm for GSEA
apeglm
fgsea
Signal-To-Noise Ratio
20 months ago
coulsonr
• 10
• updated 20 months ago
Michael Love
31k
2
Votes
1
Reply
248
Views
Deactivate svalue=T in lfcShrink - DESeq2 - apeglm
deseq2
apeglm
21 months ago
ATpoint
• 390
• updated 21 months ago
Michael Love
31k
2
Votes
4
Replies
360
Views
What is the biological meaning of genes with FC = 0 after shrinkage
deseq2
apeglm
22 months ago
polyptwo
• 0
• updated 22 months ago
Michael Love
31k
0
Votes
2
Replies
917
Views
DESeq2 coefficients for APEGLM-shrinkage
deseq2
apeglm
2.2 years ago
zolotaryovgl
• 0
• updated 2.2 years ago
Michael Love
31k
4
Votes
4
Replies
754
Views
Unexpected MAplot after apeglm shrinkage in DESeq2
apeglm
deseq2
rna-seq
2.2 years ago
ATpoint
• 390
• updated 2.2 years ago
Michael Love
31k
4
Votes
2
Replies
917
Views
Interpreting the results from lfcShrink() with apeglm in DESeq2
deseq2
apeglm
lfcshrink
2.3 years ago
charles.foster
• 100
• updated 2.3 years ago
Michael Love
31k
1
Vote
4
Replies
631
Views
Log2 fold-change shrinkage fails with lfcShrink when using the 'apeglm' method
deseq2
apeglm
lfcshrink
2.5 years ago
coulsonr
• 10
0
Votes
4
Replies
306
Views
Error in Apeglm Method for Effect Size Shrinkage
deseq2
apeglm
2.6 years ago
rbenel
• 10
• updated 2.6 years ago
Michael Love
31k
9
Votes
6
Replies
1.7k
Views
Log2FoldChange shrinkage method in DESeq2
deseq2
apeglm
lfcshrink
2.7 years ago
Benjamin Ostendorf
• 90
• updated 2.7 years ago
Michael Love
31k
23 results • Page
1 of 1
Recent ...
Replies
Answer: The compare result is different in score and Conc in DiffBind
by
shangguandong1996
• 20
I know in newer DiffBind version, the default of `score` argument is different, So I post a newer DiffBind version result. ``` library(…
Answer: Conc_1 in differnet dba.report result is slightly different
by
shangguandong1996
• 20
For a newer DiffBind version ``` library(DiffBind) library(BiocParallel) library(dplyr) tamoxifen <- dba(sampleSheet="tamoxifen.csv") ta…
Comment: Conc_1 in differnet dba.report result is slightly different
by
shangguandong1996
• 20
Hi, Dr Stark I just find you fixed the link, and I want to use the test data to reproduce my issue ``` library(DiffBind) library(BiocPara…
Comment: DESeq2 and shrinkage of log2 fold changes
by
Asier
• 0
One question related to this. In the case of using the schrinkage (in my dataset of miRNA-seq) the number of SDE miRNAs (FDR) increases wit…
Comment: [Limma] Correcting Dye swap effect
by
MatthewP
• 0
Hello, Can you explain "M vs M plot" with more details? I have include dye-effect in limma design model, and got very few probes differenti…
Votes
A: Performing differential gene analysis on RT PCR experimental data
A: Performing differential gene analysis on RT PCR experimental data
Comment: DESeq2: Significant padj and LFC in a 0 vs. 20 counts comparison?
A: Using the plotting functions of clusterProfiler / enrichplot with enrichment res
Comment: DESeq2: Significant padj and LFC in a 0 vs. 20 counts comparison?
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