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Comment: DESeq2 and shrinkage of log2 fold changes
by
Michael Love
31k
What do you mean that the set with FDR bound increases? Shrinkage methods in current versions of DESeq2 do not change the FDR (`padj` colum…
Answer: The compare result is different in score and Conc in DiffBind
by
shangguandong1996
•
20
I know in newer DiffBind version, the default of `score` argument is different, So I post a newer DiffBind version result.
```
library(…
Answer: Conc_1 in differnet dba.report result is slightly different
by
shangguandong1996
•
20
For a newer DiffBind version
```
library(DiffBind)
library(BiocParallel)
library(dplyr)
tamoxifen <- dba(sampleSheet="tamoxifen.csv")
ta…
Comment: Conc_1 in differnet dba.report result is slightly different
by
shangguandong1996
•
20
Hi, Dr Stark
I just find you fixed the link, and I want to use the test data to reproduce my issue
```
library(DiffBind)
library(BiocPara…
Comment: DESeq2 and shrinkage of log2 fold changes
by
Asier
•
0
One question related to this. In the case of using the schrinkage (in my dataset of miRNA-seq) the number of SDE miRNAs (FDR) increases wit…
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