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Question: clusterProfiler - Non model organism
1
gravatar for rozanskide
5 months ago by
rozanskide10
rozanskide10 wrote:

Dear all,

I found clusterprofiler neat and really want to give it a try. However, Im working on a non model organism and without kegg database annotation but with custom compiled kegg representatives for the model.

Is it possible to work with custom kegg annotation using clusterprofiler? Can I provide the custom annotation and then do say kegg enrichment using this custom annotation as reference?

 

Thanks

AndreiR

ADD COMMENTlink modified 5 months ago by Guangchuang Yu960 • written 5 months ago by rozanskide10
2
gravatar for Guangchuang Yu
5 months ago by
Hong Kong
Guangchuang Yu960 wrote:

clusterProfiler do support non model organisms. For GO you can use AnnotationHub to query GO annotation. For KEGG, it supports all organisms available in KEGG database as it use the online data, see http://guangchuangyu.github.io/2015/02/kegg-enrichment-analysis-with-latest-online-data-using-clusterprofiler/.

If you have customized annotation data, you can also use clusterProfiler to perform ORA or GSEA, please refer to http://guangchuangyu.github.io/2015/05/use-clusterprofiler-as-an-universal-enrichment-analysis-tool/.

ADD COMMENTlink written 5 months ago by Guangchuang Yu960
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