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Question: exomeCopy Posterior Probabilities
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gravatar for sruddy17
17 days ago by
sruddy170
sruddy170 wrote:

Hey there,

Using exomeCopy for CNV detection. Was wondering how to get the posterior probabilities that determine the path. I thought that the vector, "V", returned by the C function inside viterbiPath() was what I was looking for but when I calculate the most likely path using "V" it differs in a handful of exons/targets from what is returned by viterbiPath(). Do I need to multiply "V" by something to get the posteriors?

Thanks!

ADD COMMENTlink modified 17 days ago by Michael Love15k • written 17 days ago by sruddy170
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gravatar for Michael Love
17 days ago by
Michael Love15k
United States
Michael Love15k wrote:

We only return the Viterbi path. But you have the ‘log.odds’ vector as well, from ?”ExomeCopy-class”:

“the log ratio of the emission probabilities along the predicted path over the emission probabilities of the normal state”

ADD COMMENTlink written 17 days ago by Michael Love15k
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