Search
Question: correlated known batch effect correction using svaseq
0
gravatar for burcu.atasu
8 months ago by
burcu.atasu0 wrote:

Hi!

I've been performing RNAseq analysis by using svaseq package for batch effect correction. I have identified two slightly correlated known batch effect variables (such as; flowcell, date of data prep.). My question is if I use those two  correlated (r=0.81) known batch effect varaibles in my models, I would overcorrect the data, or since they are slightly correlated I should use both of them and sva would take this into consideration. 

 

Thank you in advance.

 

Best,

Burcu

ADD COMMENTlink written 8 months ago by burcu.atasu0
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.2.0
Traffic: 266 users visited in the last hour