I wanna check whether cn.mops is appropriate for a ~8M region of targeted sequencing.
I wanna call CNV for hybrid capture sequencing data of one contiguous targeted region (~8M), but have no idea whether cn.mops is suitable.
I have 19 cases (not tumor) and 2 controls (not match normal). For cn.mops, "recommend to useat least 6 samples for proper parameter estimation." In this case, can I still use cn.mops to call CNV? or any additional matters to be noticed?
Thanks in advance!