Question: Fold Change and LogFC
gravatar for rkp
11 months ago by
rkp0 wrote:

Hi everyone,

What is the difference between Fold Change and LogFC?. Why it is important?

Thanking you.

Kind regards,

microarray limma • 241 views
ADD COMMENTlink modified 11 months ago by James W. MacDonald48k • written 11 months ago by rkp0
Answer: Fold Change and LogFC
gravatar for James W. MacDonald
11 months ago by
United States
James W. MacDonald48k wrote:

To answer your question requires a tautology. The difference between fold change and log fold change is in the latter case the fold change has been logged. It's not important per se; it arises because most high throughput data tends to be highly right skewed, and taking logs helps with that.

ADD COMMENTlink written 11 months ago by James W. MacDonald48k
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