Question: Differential Coexpression Analysis
0
gravatar for hkarakurt
17 months ago by
hkarakurt20
hkarakurt20 wrote:

Hello everyone,

I want to do a differential coexpression analysis to a microarray data. My data have rows for genes and columns for conditions. 30 control and 28 disease columns. 

I checked some packages such as WGCNA but I think they don't take expression data as input.

Anyone has any advice, tutorial or another package to do it?

 

Thanks.

ADD COMMENTlink modified 17 months ago by Peter Langfelder2.1k • written 17 months ago by hkarakurt20
Answer: Differential Coexpression Analysis
0
gravatar for Peter Langfelder
17 months ago by
United States
Peter Langfelder2.1k wrote:

Searching for "differential coexpression" brings out several articles describing different ways of doing a differential co-expression analysis.

WGCNA is not designed for gene-level differential co-expression analysis, but you can certainly study preservation of modules as well as common (consensus) modules for two or more data sets. Oh, and WGCNA certainly takes expression data as input... perhaps you meant something else?

 

ADD COMMENTlink written 17 months ago by Peter Langfelder2.1k
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