Question received via GitHub https://github.com/Oshlack/splatter/issues/41
I was trying to simulate a differentiation, and followed the instructions for paths in Introduction to Splatter. However, when I then looked at the data with
assay(sim.paths), I was greeted by a matrix where all columns (cells) had identical values. Am I doing something wrong? I was hoping to eventually simulate more complex lineage trees.
The code in question:
library(splatter) sim.paths <- splatSimulate(method = "paths", verbose = FALSE) sim.paths <- normalise(sim.paths) View(assay(sim.paths))