I got the following plot for one of the DE genes. The p-value in DP cell type (the most right panel) is 7.50e-07 (FDR = 3.04e-05), with log2(fold-change) of 30. But obviously it's caused by the two outlier samples on the right corner. How would I avoid reporting genes like this? I am not sure the two outlier samples are same for other genes, so filtering them with minReplicateForReplace=Inf might not be an ideal solution.
I am using DESeq2_1.16.1.