Thank you for all support so far.
I was looking back at previous posts, but couldn't find any question , so I will ask:
Is it possible to change metadata associated with dba object after dba.counts call. I am trying to understand my principal components better, and for that I would need more associated data. I could not find a way how to add extra data, so I wondered if it is possible to change existing data for Tissue or Replicate?