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ZihaoXing
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@zihaoxing-13254
Last seen 5.1 years ago

i found that the fold change of different RNAseq expression analyse resultsĀ in edgeR is logFC, log2FC is also often used in other analysed ,i want to know if the logFC is same as log2FC in edgeR ,or it is based on exp(1).

thanks ,i hope it can be changed into log2FC in edgeR in future ,otherwise, it is easy to be confused ,because log default as loge rather than log2 in math.

I prefer the more concise logFC notation and I don't think there's any ambiguity in the edgeR context. Any of the edgeR help pages will tell you that the fold-changes are log2.

log typically means log2 in both computer science and bioinformatics, and the standard international notation for loge is ln() rather htan log() (https://en.wikipedia.org/wiki/Logarithm) so I don't think you can be pedantic that log means loge.