Question: Sva for tumor cellular heterogeneity
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gravatar for chp950
6 months ago by
chp9500
chp9500 wrote:

 

Hi,

We are analyzing tumor expression data, and thought cellular heterogeneity would be a source of unwanted biological variations. We thought to adjust for cellular heterogeneity using sva, however, we noticed the leek method produced different answers compared to the be method. How could one choose how many surrogate variables to include? 

Thanks!

limma sva • 116 views
ADD COMMENTlink written 6 months ago by chp9500
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