Hi all,

I'm very new to using GenomicFeatures and I'm trying to download a NCBI hg38 transcript annotation package (I want to use the built in functions such as promoters() etc).

Can someone direct me to where I can get this?

I have tried

> makeTxDbFromBiomart

but this isn't working for me and I get a timed out message (I'm not sure if this is actually the way to do it)

library(BiocInstaller)
biocLite("TxDb.Hsapiens.UCSC.hg38.knownGene")

If you use makeTxDbFromBiomart, you get a TxDb based on EBI/EMBL mappings, which is not the same as NCBI. UCSC is technically not the same either, but it is very close, and one could argue a bit cleaner.