Question: SomaticSignatures package: how can I get probability of certain mutation type within a signature?
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gravatar for spr
5 months ago by
spr0
spr0 wrote:

Hello,

I am using SomaticSignatures to extract mutational signatures from my .maf files and in the signature plot, I have noticed that the y axis does not represent probability of mutation type within this particular signature, as the upper limit is well above 1. It rather represents "contribution", I am guessing. Signatures have been calculated through NMF. Is it possible to calculate that probability?  

Thanks!

 

 

somaticsignatures • 103 views
ADD COMMENTlink written 5 months ago by spr0
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