Question: DESeq2 standard error estimate (lfcSE)
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gravatar for shintzen
5 months ago by
shintzen0
shintzen0 wrote:

I have quite a few results of DESeq2 where the lfcSE is very near to 1. I don't fully understand how I should interpret this value, and though I have read through the first several pages of google with a few different search terms, I am still not confident that I fully understand.

From what I've understood you can convert these to fold change errors using this formula: 2^(coef - SE) and 2^(coef + SE) and if you multiple lfcSE by normal quantiles (e.g. qnorm(.025)), you can construct confidence intervals for the coefficients but I still don't know how to apply that information to my experiment. Should I disregard anything where the lfcSE is near 1?

I am happy to be pointed to some good descriptions of this value, outside of the R Documentation.

deseq2 • 138 views
ADD COMMENTlink modified 5 months ago by Michael Love24k • written 5 months ago by shintzen0
Answer: DESeq2 standard error estimate (lfcSE)
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gravatar for Michael Love
5 months ago by
Michael Love24k
United States
Michael Love24k wrote:

Can you show some examples of this lfcSE near 1?

ADD COMMENTlink written 5 months ago by Michael Love24k
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