Hi, I am working on a project where i have to link the probes of different microarray platforms (Affymetrix, Agilent, ABI Gene, Illumina). I would like to know or this is possible with Bioconductor\R. I can get the annotation files of the manufacturers where for each probe the Genbank id is specified. With the AnnBuilder package the genbank id's can be linked to the Unigene id's. When i create a package for each platform, i thougth it would be possible to get the overlapping probes by selecting the UniGene identifiers that are pressent in each platforms. Is this possible with the Annotate package? I saw things like the get and multiget functions, but can these functions also be used with multiple packages? The result has then to be visualised in a Venn Diagram (i saw examples in a few articles) and a spreadsheet listing all overlapping probes. I am relatively new to R/Bioconductor, so i would like to know the above is possible with the AnnBuilder and Annotate packages. Maybe someone can give me some hints to get started? Thanks M. de Hollander P.S. I am sorry for the duplicate message. This one is now in plain text. -- Student Bio-Informatics Hogeschool Leiden The Netherlands