Useful of Normal Enrichment Score (NES) in GSEA
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@aboumarshal-19661
Last seen 5.2 years ago

I know how NES is calculated in GSEA method using ClusterProfiler. But I don't understand its utility ?

I have read some where (in borad institute paper) that NES is used to calculated the false discovery rate (FDR). So in ClusterProfiler how NES is used ? And how p.adjsut ise calculated ?

Thank you.

GSEA • 2.4k views
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You can refer to this post about GSEA in another forum.

I hope it helps.

Best, Mikhael

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