I am interested in using diffbind to perform differential expression analysis on some ATAC data. However, all I have is counts table for peaks (no beds or bams) and a meta table with the sample names and conditions they belong to. Is there a way to use diffbind from here and is there any benefit over simply using DESeq2 or edgeR?
Thanks for the help in advance!
Fake example table
peakname condition1r1 condition1r2 condition2r1 condition2r2
peak1 19 21 29 31
peak2 34 30 15 17