Hi,

I don't know how to solve this error in installing DESeq2

Any help please?

> library(DESeq2)
Loading required package: GenomicRanges
Error: package ‘S4Vectors’ 0.18.1 is loaded, but >= 0.19.11 is required by ‘GenomicRanges’
In addition: Warning message:
package ‘DESeq2’ was built under R version 3.5.2 
>

Thank you

You will need to update the version of S4Vectors. You can check which packages are available and need updating by doing

BiocManager::valid()

It will list any packages that need updating and the command that should be run. At the very least you should update and re-install S4Vectors and probably GenomicRanges.

BiocManager::install(c("S4Vectors", "GenomicRanges", "DESeq2"))