I'm new to this so apologies if my question is very simple....
I conducted DESeq2 anlaysis for some 16S rRNA sequencing data. I compared the differentially expressed genes between two time points.
Example results for one OTU is below, so a log2 fold increase of 24.2 from timepoint 1 to 2. Please can someone explain what this actually means? And also what the base mean is?
My supervisor made this comment and now i am unsure of what my results are actually saying - "I think you are referring to a 24 fold increment in numbers aren’t you or is the start log 0.1? If for example they start at log 2.0, or 100 cfu/g, then a 24 fold increment would take it to log 48. It may be more useful to identify where you are going to and from where – eg log 1 to log 6 – as this is more interpretable".
OUT baseMean = 17.61369762
log2FoldChange = 24.21197847 lfcSE = 1.796033089 stat =13.48080869 pvalue = 2.03E-41 padj = 6.84E-38 Genus = Veillonella
If someone could get abck to me ASAP, id be so grateful :)