Question: DESeq2 excess of positive signals
0
gravatar for mesaez
3 months ago by
mesaez0
mesaez0 wrote:

Hi all I'm working with DEseq2 on RNAseq data and I observe an excess of positive signals (see attached MA plot). Any idea about how to reduce the noise? Many thanks in advance Maria

MA plot

deseq2 • 67 views
ADD COMMENTlink modified 3 months ago by Michael Love24k • written 3 months ago by mesaez0
Answer: DESeq2 excess of positive signals
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gravatar for Michael Love
3 months ago by
Michael Love24k
United States
Michael Love24k wrote:

Use an lfcThreshold to define biological significance, for motivation read the DESeq2 paper or vignette on threshold testing.

ADD COMMENTlink written 3 months ago by Michael Love24k
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