I'm looking through the RUVseq manual and it seems that the
set object used for RUVg normalization has first been normalized using
betweenLaneNormalization from EDASeq? I tried RUVg normalization both with and without doing
betweenLaneNormalization first and I get different results. So I just wanted to confirm whether it's recommended to do
betweenLaneNormalization before RUVg normalization?