Question: scATAC-seq analysis, data preprocessing
0
gravatar for chipolino
4 months ago by
chipolino0
chipolino0 wrote:

Hi,

During scATAC-seq data preprocessing, does it make sense to filter data matrix, so it contains only most variable peaks (in the same way how we do it for scRNA-seq), before any further dimensionality reduction or clustering analysis?

Thanks

scatac-seq • 123 views
ADD COMMENTlink modified 4 months ago by Aaron Lun24k • written 4 months ago by chipolino0

Cross-posted on Biostars as suggested by Aaron.

ADD REPLYlink modified 4 months ago • written 4 months ago by ATpoint20
Answer: scATAC-seq analysis, data preprocessing
0
gravatar for Aaron Lun
4 months ago by
Aaron Lun24k
Cambridge, United Kingdom
Aaron Lun24k wrote:

You're not asking about a specific Bioconductor package; a general question should be posted on a more general forum like Biostars. But for what it's worth, the answer is: probably yes.

ADD COMMENTlink written 4 months ago by Aaron Lun24k
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