Question: The correct specification of the model matrix to ComBat
0
gravatar for Samuel
8 weeks ago by
Samuel0
Samuel0 wrote:

When using the ComBat function for batch correction, what is the difference between the following two specifications of the matrix model :

mod <- model.matrix(~1, dat=colData)
mod <- model.matrix(~ ConditionOfInterest, dat=colData)

When calling

ComBat(dat=expressionMatrix, batch=colData$Batch,  mod = mod)
sva combat • 70 views
ADD COMMENTlink written 8 weeks ago by Samuel0
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