The correct specification of the model matrix to ComBat
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Sam ▴ 10
@sam-21502
Last seen 16 hours ago
Jerusalem

When using the ComBat function for batch correction, what is the difference between the following two specifications of the matrix model :

mod <- model.matrix(~1, dat=colData)
mod <- model.matrix(~ ConditionOfInterest, dat=colData)

When calling

ComBat(dat=expressionMatrix, batch=colData$Batch,  mod = mod)
ComBat sva • 257 views
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