I am trying to run the following codes from AnnBuilder Vignette in R 2.2.1 under Windows XP, ###################################################################### ### library(AnnBuilder) read.table(file.path(.path.package("AnnBuilder"),"data","thgu95a"),sep ="\t", header=FALSE,as.is=TRUE) myBase<-file.path(.path.package("AnnBuilder"), "data", "thgu95a") myBaseType<-"gb" mySrcUrls<-c(LL="http://www.bioconductor.org/datafiles/wwwsources/Tll_ tmpl.gz", UG="http://www.bioconductor.org/datafiles/wwwsources/Ths.data.gz", GO="http://www.bioconductor.org/datafiles/wwwsources/Tgo.xml") read.table(file.path(.path.package("AnnBuilder"), "data", "srca"), sep="\t", header=FALSE,as.is=TRUE) read.table(file.path(.path.package("AnnBuilder"), "data", "srcB"), sep="\t", header=FALSE,as.is=TRUE) myOtherSrc<-c(srcone=file.path(.path.package("AnnBuilder"), "data", "srca"), srctwo=file.path(.path.package("AnnBuilder"), "data","srcb")) myDir<-tempdir() ABPkgBuilder(baseName=myBase, srcUrls=mySrcUrls, baseMapType=myBaseType, otherSrc=myOtherSrc, pkgName="myPkg", pkgPath=myDir, organism= "Homo sapiens", version="1.1.0", author=list(author="myname", maintainer="myname at myemail.com"), fromWeb=TRUE) ###################################################################### And I got an error message, Warning message: cannot open: HTTP status was '404 Not Found' Error in loadFromUrl(srcUrls[i]) : URL http://www.bioconductor.org/datafiles/wwwsources/Ths.data.gz is incorrect or the target site is not responding! So I delete UG="http://www.bioconductor.org/datafiles/wwwsources/Ths.data.gz", from mySrcUrls and run again, and this time I got another error message, Error in "baseFile<-"(`*tmp*`, value = "C:\\DOCUME~1\\Owner\\LOCALS~1\\Temp/Rtmp2j5Apb\\tempFile5f906952") : no direct or inherited method for function 'baseFile<-' for this call I found that myDir is "C:\\DOCUME~1\\Owner\\LOCALS~1\\Temp/Rtmp2j5Apb" I change myDir to "C:\\DOCUME~1\\Owner\\LOCALS~1\\Temp/Rtmp2j5Apb\\tempFile5f906952" and got an error message Error in "baseFile<-"(`*tmp*`, value = "C:\\DOCUME~1\\Owner\\LOCALS~1\\Temp/Rtmp2j5Apb\\tempFile6df11649") : no direct or inherited method for function 'baseFile<-' for this call Could someone tell me how to solve this problem? Thanks Mary