I'm currently using WGCNA v1.68 to do network analysis on 50k probes. I have a few questions regarding parallelization in WGCNA, particularly running the blockwiseModules and TOMsimilarity functions. I came across another bioconductor question on this topic (https://support.bioconductor.org/p/86147/), but it was from 3 years ago, so I was wondering if there's any updates that I should be aware of?
In the previous questioned, Peter said that blockwiseModules was not parallelized, has this changed? He kindly suggested using an faster BLAS to speed up matrix multiplication in TOM calculations, currently my output when running TOMsimilarity() is showing "..matrix multiplication (system BLAS)..", so I'm guessing the system BLAS is not the fast BLAS Peter's referring to? Does anyone know which fast BLAS I should try installing? (I'm currently using R on a CentOS server with up to 50 cores).
I already tried setting "enableWGCNAThreads(nThreads = 50)", but I don't think it did anything.
Much thanks for any help anyone can provide,