how to find consensus modules between 2 datasets by different platform through WGCNA
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modarzi ▴ 10
Last seen 2.9 years ago

Dear All,

I know the tutorial of WGCNA for consensus modules. Now, I have two datasets for Breast cancer in which one of them is based on a microarray platform and another is RNA-seq based on the Illumina platform. Originally, the gene list in two datasets isn't identical and they have normalized through different normalization methods. E.g, the microarray dataset was normalized through RMA and RNA-seq has been normalized by the TPM method. My question is how can I find consensus modules between two of that datasets? is its rationale for finding consensus modules between them?

I appreciate it if anybody shares his/her comment with me.

consensusmodule microarray RNA-seq WGCNA • 1.1k views

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