We are trying to process mouse affy chip data using bioconductor. We have bioconductor installed and it works on Drosophila chips, however we cannot get it to recognize the mouse .cdf files. We have tried downloading the files and unzipping them several ways, but each time we try to process our data the program can't find the cdf files even though they are in the same directory as the data files. Do we need to install the cdf files in some special way? We tried R CMD INSTALL, but couldn't get it to work. Does anyone out there have an idea what our problem is? Thanks, Nancysomnath Dr. Nancy S. Petersen, Professor Department of Molecular Biology University of Wyoming Laramie, WY 82071-3944 Tel. (307) 766-4806 Fax. (307) 766-5098 Email: petersen@uwyo.edu http://www.uwyo.edu/ag/MOLECBIO/petersen.html