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Brooke-Powell, Elizabeth
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170

@brooke-powell-elizabeth-1185
Last seen 7.4 years ago

Dear list,
I am wondering if you would be able help me with a problem I seem to
be
experiencing using SAM (v2.20a). I am using it through the Excel add-
in, but
the question I have is not a technical computer or programming problem
(to
my knowledge) but one about the analysis itself.
When I am performing oneclass analysis of ratio data from a microarray
experiment it seems that the oneclass analysis only likes to have odd
numbers of data columns where each data column is a list of ratios for
one
slide in an experiment. I can get analysis done for 3,5,7,9,and 11
slides of
data, but not 2,4,6,8,10 or 12. I am wondering if I am missing
something
about oneclass analysis, but it seems to me that you would want a
balanced
design of an experiment with even numbers of slides.
Any help would be appreciated, I have tried contacting the SAM list
which is
next to useless.
Happy New Year to everyone,
Liz Brooke-Powell
Washington University Medical School,
Department of Molecular Microbiology,
CB#8230, 660 S. Euclid Ave
St. Louis, MO, 63110