On Friday 13 April 2007 03:51, gregory voisin wrote:
> Hi Bioconductorians, Bioconductoriannes,
> My question : on website of bioconductor , I find the package:
> hgu133plus2... ( I go in R ...blabla: library (hgu133pluss, then
> (packages: hgu133plus2).....and here more information than in
> affy_annatation file ( I think ).... But this pacakge is developped
> Biocore team core.... Who is Biocore team core? ( on Google, no
> precise information ) . I would like to know how are these
> created, which data origine , which frequency update....???
The package hgu133plus2 is maintained by our team at the Department of
computational biology at Fred Hutchinson Cancer Research Center at
We are part of the biocore team (i.e. the core team of bioconductor).
package is updated once every six months by using another R package
AnnBuilder. You can think hgu133plus2 as a product of AnnBuilder. The
of AnnBuilder provides al the details of this package producing
The hgu133plus2 package in bioconductor 2.0 repository was created
about a month
ago. All the source data was downloaded on Feb 28, 2007. The lastest
annotation file at that time was dated as Nov 15, 2006 (Affymetrix
newer version on Marth 9). We will update it again about 6 month
before next bioconductor release.
If you think the source data is old, you can always create your own
by using AnnBuilder. You can start from the vignette of AnnBuilder and
on the old posts about AnnBuilder on this list.
If you want to use the hgu133plus2 in the repository, I suggest you
wait for one
or two weeks. We will provide another version of hgu133plus2 which
data in a sqlite file (google for SQLite). It might be easier for your
can import the sqlite data into a database and do the comparison there
going through the R layer.
PS: "??? and blabal" is not friendly IMO.
Public Health, Fred Hutchinson Cancer Research Center
Seattle, WA 98109