"ruma" <rumas at="" cdac.in=""> writes: > Hi > > I have installed R-2.5.0 on Linux(Redhat Enterprise 64bit o.s.) and have > been trying to install the > BioConductor packages without success. > > when I try to access the packages i get the following error: > >> source("http://bioconductor.org/biocLite.R") > Error in file(file, "r", encoding = encoding) : > unable to open connection > In addition: Warning message: > unable to connect to 'bioconductor.org' on port 80. > I tried looking at the posts and tried using the To get R to connect to the > proxy server, by giving the > following(which has been suggested in the posts): > > Sys.putenv("http_proxy"="http://name_of_proxy_server") > but that too gave the same error. > > Is there an easy way to overcome this problem? > I have looked at the posts and it seems to be a firewall issue. Can you > please help me solve this issue? Have a look at the man page for download.file: help("download.file") This looks like a proxy issue to me and if after reading the download.file man page and following its suggestions you don't get things working, you might post to R-help -- sorry, but what you are describing is a general R problem and not Bioconductor specific. You might also try searching the R-help list for solutions. Note in particulr this bit: These environment variables must be set before the download code is first used: they cannot be altered later by calling 'Sys.setenv'. + seth -- Seth Falcon | Computational Biology | Fred Hutchinson Cancer Research Center http://bioconductor.org