Question: Background correction and normalization for very small customized arrays
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gravatar for Bandyopadhyay, Somnath Som
12.1 years ago by

Hi, I am trying to analyze gene expression data from some customized single channel arrays having only 40 genes including control probes. I have enough replicates to work with. Can anybody suggest a method for background correction and normalization for these kind of arrays? I have around 8 slides.Even links to references would be highly appreciated. Thanks, Som.

ADD COMMENTlink modified 4.6 years ago by Gordon Smyth39k • written 12.1 years ago by Bandyopadhyay, Somnath Som60
Answer: BACKGROUND CORRECTION AND NORMALIZATION FOR VERY SMALL CUSTOMIZED ARRAYS
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gravatar for Gordon Smyth
4.6 years ago by
Gordon Smyth39k
Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
Gordon Smyth39k wrote:

The limma package provides a range of background and normalization options, some of which make use of control probes.

ADD COMMENTlink written 4.6 years ago by Gordon Smyth39k
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