I'm embarking on a GSEA analysis of a very straightforward 1 factor, 2 levels experiment. The GSEABase package appears to provide a really good starting point, although I can't find any packages that depend on the data-structure created. Is there an R implementation of the GSEA approach used by the Broad Institute? All I want is a method to compute the likelihood that the median absolute t-statistic of a group is unlikely by chance alone. For groups I'd like to use GO BP and KEGG categories. Thanks, Mark -- Mark W. Kimpel MD ** Neuroinformatics ** Dept. of Psychiatry Indiana University School of Medicine 15032 Hunter Court, Westfield, IN 46074 (317) 490-5129 Work, & Mobile & VoiceMail (317) 663-0513 Home (no voice mail please) ****************************************************************** [[alternative HTML version deleted]]