GOstats - KEGG & PFAM mappings to Entrez IDs
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Tim Smith ★ 1.1k
@tim-smith-1532
Last seen 9.6 years ago
Hi, I was using the hyperGTest in GOstats to find significant KEGG and PFAM terms. I have the entrez IDs of a set of genes and I test these with a universe of entrez IDs in hyperGTest to get the significant KEGG and PFAM terms. Now, I want to know which particular entrez IDs in my set of genes map to a particular significant KEGG/PFAM ID. I checked the KEGG.db (and PFAM.db) packages, but they don't have a KEGG ID to Entrez ID mapping. How can I get this? I guess GOstats is using a mapping of sorts in the hyperGTest, but where can I find it? thanks! [[alternative HTML version deleted]]
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@sean-davis-490
Last seen 3 months ago
United States
On Wed, Oct 15, 2008 at 7:53 AM, Tim Smith <tim_smith_666 at="" yahoo.com=""> wrote: > Hi, > > I was using the hyperGTest in GOstats to find significant KEGG and PFAM terms. I have the entrez IDs of a set of genes and I test these with a universe of entrez IDs in hyperGTest to get the significant KEGG and PFAM terms. Now, I want to know which particular entrez IDs in my set of genes map to a particular significant KEGG/PFAM ID. > > I checked the KEGG.db (and PFAM.db) packages, but they don't have a KEGG ID to Entrez ID mapping. How can I get this? I guess GOstats is using a mapping of sorts in the hyperGTest, but where can I find it? > Look at the org.Hs.eg.db package (for human). There are mappings there. Sean
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Sean Davis wrote: > On Wed, Oct 15, 2008 at 7:53 AM, Tim Smith <tim_smith_666 at="" yahoo.com=""> wrote: > >> Hi, >> >> I was using the hyperGTest in GOstats to find significant KEGG and PFAM terms. I have the entrez IDs of a set of genes and I test these with a universe of entrez IDs in hyperGTest to get the significant KEGG and PFAM terms. Now, I want to know which particular entrez IDs in my set of genes map to a particular significant KEGG/PFAM ID. >> >> I checked the KEGG.db (and PFAM.db) packages, but they don't have a KEGG ID to Entrez ID mapping. How can I get this? I guess GOstats is using a mapping of sorts in the hyperGTest, but where can I find it? >> >> > > Look at the org.Hs.eg.db package (for human). There are mappings there. > > Sean > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor > > Sean is right if you are working on human, If you need information for another species, you can look for a different "org.XX.eg.db" package where "XX" is the 1st letters of the genus and species. You can also find this information inside of the chip based annotation packages. Marc
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