Dear BioC Group, I am trying to load Rgraphviz but I keep receiving an error. I have installed graphviz 2.2. I searched the mailing list archives, and, as far as I can tell, no error like this has appeared. I tried loading Rgraphviz on two different computers running two different versions of R and BioC and received the same error. Relevant information follows. > sessionInfo() R version 2.8.0 (2008-10-20) powerpc-apple-darwin8.11.1 locale: C attached base packages: [1] grid tools stats graphics grDevices utils datasets methods base other attached packages: [1] graph_1.20.0 affy_1.20.0 Biobase_2.2.1 loaded via a namespace (and not attached): [1] affyio_1.10.1 cluster_1.11.11 preprocessCore_1.4.0 > library(Rgraphviz) Error in dyn.load(file, DLLpath = DLLpath, ...) : unable to load shared library '/Library/Frameworks/R.framework/Resou rces/library/Rgraphviz/libs/ppc/Rgraphviz.so': dlopen(/Library/Frameworks/R.framework/Resources/library/Rgraphviz/l ibs/ppc/Rgraphviz.so, 6): Library not loaded: /usr/local/lib/libgvc.3.dylib Referenced from: /Library/Frameworks/R.framework/Resources/library/R graphviz/libs/ppc/Rgraphviz.so Reason: image not found Error : .onLoad failed in 'loadNamespace' for 'Rgraphviz' Error: package/namespace load failed for 'Rgraphviz' I also tried loading Rgraphviz on an Intel-based Power PC running R 2.7.2 and received the same error: > library(Rgraphviz) Loading required package: grid Error in dyn.load(file, DLLpath = DLLpath, ...) : unable to load shared library '/Library/Frameworks/R.framework/Resou rces/library/Rgraphviz/libs/i386/Rgraphviz.so': dlopen(/Library/Frameworks/R.framework/Resources/library/Rgraphviz/l ibs/i386/Rgraphviz.so, 6): Library not loaded: /usr/local/lib/libgvc.3.dylib Referenced from: /Library/Frameworks/R.framework/Resources/library/R graphviz/libs/i386/Rgraphviz.so Reason: image not found Error : .onLoad failed in 'loadNamespace' for 'Rgraphviz' Error: package/namespace load failed for 'Rgraphviz' > sessionInfo() R version 2.7.2 (2008-08-25) i386-apple-darwin8.11.1 locale: C attached base packages: [1] grid splines tools stats graphics grDevices utils datasets [9] methods base other attached packages: [1] humanCHRLOC_2.1.4 Category_2.6.0 graph_1.18.1 KEGG.db_2.2.0 [5] hgu95av2.db_2.2.0 genefilter_1.20.0 survival_2.34-1 ALL_1.4.4 [9] GSEABase_1.2.2 annotate_1.18.0 xtable_1.5-3 AnnotationDbi_1.2.2 [13] RSQLite_0.7-0 DBI_0.2-4 Biobase_2.0.1 loaded via a namespace (and not attached): [1] RBGL_1.16.0 XML_1.96-0 cluster_1.11.11 Thanks for your help, Monnie