HI, I want to compare two daya sets for clustering: one is from two-color array with log ratio; while another is raw data from single-color agilent array. my rerult has shown they are totally seperated groups in cluster or heatmap. Anybody has got known how to normalize and combine those two different data sets togather, to compare and cluster them? Thanks, Xiang

You could try this: http://www.ncbi.nlm.nih.gov/pubmed/17116249 http://bioinformatics.iah.ac.uk/software/coxpress ________________________________________ From: bioconductor-bounces@stat.math.ethz.ch [bioconductor- bounces@stat.math.ethz.ch] On Behalf Of xiangxue Guo [xiangxue_guo@yahoo.com] Sent: 30 October 2009 20:27 To: bioconductor Subject: [BioC] Comparing/clustering data sets from two-color and single color array HI, I want to compare two daya sets for clustering: one is from two-color array with log ratio; while another is raw data from single-color agilent array. my rerult has shown they are totally seperated groups in cluster or heatmap. Anybody has got known how to normalize and combine those two different data sets togather, to compare and cluster them? Thanks, Xiang _______________________________________________ Bioconductor mailing list Bioconductor at stat.math.ethz.ch https://stat.ethz.ch/mailman/listinfo/bioconductor Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor