Hi I am trying to call up a program called xcms in R (using Centos version of linux), but keep getting the following error message: > library(xcms) Error in dyn.load(file, DLLpath = DLLpath, ...) : unable to load shared library '/usr/lib/R/library/xcms/libs/xcms.so': /usr/lib/R/library/xcms/libs/xcms.so: cannot restore segment prot after reloc: Permission denied Error: package/namespace load failed for 'xcms' I have tried loading other R supported packages from bioconductor and they load fine, so this doesnt seem to be an R problem , but one with proper xcms installation. I installed xcms through the bioconductor xcms site, as they recommend (directly through R), and the installation seemed to have gone fine. No errors during installation, and all the xcms directories and files seem to be in the correct location. I have already posted this on the xcms forum but no one had any suggestions. Has anyone seen this error and have any idea what may be wrong? thank you ilya