Hello, I am interested in using the package clusterStab and in particular the clusterComp function as a way to test the stability of the clustering of the dendrograms I have produced from microarray data. The problem I have is that I would like to use a correlation distance (1-cor()) and it appears that the only option is to use a Euclidean distance. Is that correct? Is there a way to alter the input data so that a Euclidean distance is in effect a correlation distance? If not would is be easy to change the source of the function? Many Thanks Dan -- ************************************************************** Daniel Brewer, Ph.D. Institute of Cancer Research Molecular Carcinogenesis Email: daniel.brewer at icr.ac.uk ************************************************************** The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP. This e-mail message is confidential and for use by the a...{{dropped:2}}

Hi Daniel, Daniel Brewer wrote: > Hello, > > I am interested in using the package clusterStab and in particular the > clusterComp function as a way to test the stability of the clustering of > the dendrograms I have produced from microarray data. The problem I > have is that I would like to use a correlation distance (1-cor()) and it > appears that the only option is to use a Euclidean distance. Is that > correct? Yes, the only option is to use Euclidean distance. > > Is there a way to alter the input data so that a Euclidean distance is > in effect a correlation distance? No, the distance matrix is computed internally, so inputting anything but a matrix of data will just make a mess of things. > > If not would is be easy to change the source of the function? Sure. Just download the source package, make whatever changes you want, and then build and install. Best, Jim > > Many Thanks > > Dan > ********************************************************** Electronic Mail is not secure, may not be read every day, and should not be used for urgent or sensitive issues