Muhammad, Please update your R and Bioconductor installation to the most recent release (Bioconductor 2.7 and R 2.12.0) that should resolve the issue. Best regards, Julie On 12/28/10 12:20 AM, "muhammed shafi" <safee86@gmail.com> wrote: Respected Madam, I am new to bioinformatics and bioconductor I am using R version 2.9.2 through linux(ubuntu) and bioconductor version2.4. While I am trying to download ChIPpeakAnno package by giving following command >source("http://www.bioconductor.org/biocLite.R") >biocLite("ChIPpeakAnno") its giving an error saying ""Warning in install.packages(pkgs = pkgs, repos = repos, dependencies = dependencies, : argument 'lib' is missing: using '/home/mlscubl11/R/i486-pc-linux- gnu-library/2.9' Warning message: In getDependencies(pkgs, dependencies, available, lib) : package ‘ChIPpeakAnno’ is not available"" . Please help me to find out the problem. i am really sorry for mistakes in language. thanking you Muhammad shafi [[alternative HTML version deleted]]