Could someone please help me out with getting snapCGH to work? Installation of snapCGH and its dependencies didn't suggest any problems but when I try to load snapCGH I get the error below. I would email the authors of this package but I haven't been able to find their email addresses. Thanks for any help! Windows vista: > library(snapCGH) Error in inDL(x, as.logical(local), as.logical(now), ...) :   unable to load shared library 'c:/PROGRA~1/R/R-2.11.1/library/GLAD/libs/GLAD.dll':   LoadLibrary failure:  The specified module could not be found. Error: package/namespace load failed for 'snapCGH' > sessionInfo() R version 2.11.1 (2010-05-31) i386-pc-mingw32 locale: [1] LC_COLLATE=English_Canada.1252  LC_CTYPE=English_Canada.1252 [3] LC_MONETARY=English_Canada.1252 LC_NUMERIC=C [5] LC_TIME=English_Canada.1252 attached base packages: [1] stats     graphics  grDevices utils     datasets  methods   base other attached packages: [1] DNAcopy_1.22.1     limma_3.4.5        MASS_7.3-6 lme4_0.999375-35 [5] Matrix_0.999375-39 lattice_0.18-8     xtable_1.5-6 loaded via a namespace (and not attached):  [1] aCGH_1.26.0     Biobase_2.8.0   cluster_1.12.3  grid_2.11.1  [5] multtest_2.7.1  nlme_3.1-96     splines_2.11.1  stats4_2.11.1  [9] survival_2.35-8 tools_2.11.1 > [[alternative HTML version deleted]]

On 02/24/2011 04:38 PM, Gregory Gentlemen wrote: > Could someone please help me out with getting snapCGH to work? Installation of snapCGH and its dependencies didn't suggest any problems but when I try to load snapCGH I get the error below. I would email the authors of this package but I haven't been able to find their email addresses. > > Thanks for any help! > > Windows vista: > >> library(snapCGH) > Error in inDL(x, as.logical(local), as.logical(now), ...) : > unable to load shared library 'c:/PROGRA~1/R/R-2.11.1/library/GLAD/libs/GLAD.dll': > LoadLibrary failure: The specified module could not be found. Hi Greg -- The problem is likely with the GLAD package. The GLAD package DESCRIPTION file (not that this is easy to find!) has SystemRequirements: gsl. Note: users should have GSL installed. Windows users: 'consult the README file available in the inst directory of the source distribution for necessary configuration instructions'. The mentioned file is available in the 'tar.gz' file mentioned on page http://bioconductor.org/help/bioc-views/release/bioc/html/GLAD.html which says You need the GNU Scientific Library (GSL) for the GLAD package. Make sure it is installed on your machine if you want to use GLAD. GSL is free and can be downloaded at http://www.gnu.org/software/gsl/ for unix distributions and at http://gnuwin32.sourceforge.net/packages/gsl.htm for Windows. Windows users ============= To install a pre-built binary of GLAD and to load the package successfully you need to tell R where to link GSL. You can do that by adding /path/to/libgsl.dll to the Path environment variable. To add this you may right click on "My Computer", choose "Properties", select the "Advanced" tab, and click the button "Environment Variables". In the dialog box that opens, click "Path" in the variable list, and then click "Edit". Add /path/to/libgsl.dll to the Variable value field. It is important that the file path does not contain any space characters; to avoid this you may simply use the short forms (8.3 DOS file names) found by typing "dir /x" at the Windows command line. For example, I added the following on my Windows machine: C:/PROGRA~1/GNUWIN32/bin and used ";" to separate it from existing paths. The file goes on to discuss building from source, but that is not relevant to you. Hope that helps. Martin > Error: package/namespace load failed for 'snapCGH' >> sessionInfo() > R version 2.11.1 (2010-05-31) > i386-pc-mingw32 > > locale: > [1] LC_COLLATE=English_Canada.1252 LC_CTYPE=English_Canada.1252 > [3] LC_MONETARY=English_Canada.1252 LC_NUMERIC=C > [5] LC_TIME=English_Canada.1252 > > attached base packages: > [1] stats graphics grDevices utils datasets methods base > > other attached packages: > [1] DNAcopy_1.22.1 limma_3.4.5 MASS_7.3-6 lme4_0.999375-35 > [5] Matrix_0.999375-39 lattice_0.18-8 xtable_1.5-6 > > loaded via a namespace (and not attached): > [1] aCGH_1.26.0 Biobase_2.8.0 cluster_1.12.3 grid_2.11.1 > [5] multtest_2.7.1 nlme_3.1-96 splines_2.11.1 stats4_2.11.1 > [9] survival_2.35-8 tools_2.11.1 >> > > > > [[alternative HTML version deleted]] > > > > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor -- Computational Biology Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N. PO Box 19024 Seattle, WA 98109 Location: M1-B861 Telephone: 206 667-2793