Hi All any one encountered this error before ? I have the following error when using pvlcust for a transposed matrix. Please advise how I can get bp/au values when clustering by rows ? Looking forward to your reply Thanks a lot yours, Alyaa pv <- pvclust(as.matrix(t(bb)), method.dist="correlation", method.hclust="complete", nboot=10) Error in solve.default(crossprod(X, X/vv)) : Lapack routine dgesv: system is exactly singular In addition: There were 11 warnings (use warnings() to see them) Warning messages: 1: inappropriate distance matrices are omitted in computation: r = 0.5 2: inappropriate distance matrices are omitted in computation: r = 0.5 3: inappropriate distance matrices are omitted in computation: r = 0.5 4: inappropriate distance matrices are omitted in computation: r = 0.75 5: inappropriate distance matrices are omitted in computation: r = 0.75 6: inappropriate distance matrices are omitted in computation: r = 1 7: inappropriate distance matrices are omitted in computation: r = 1 8: inappropriate distance matrices are omitted in computation: r = 1 9: inappropriate distance matrices are omitted in computation: r = 1.25 10: inappropriate distance matrices are omitted in computation: r = 1.25 11: In lsfit(X, zz, 1/vv, intercept = FALSE) : 'X' matrix was collinear -- Alyaa Mahmoud "Love all, trust a few, do wrong to none"- Shakespeare -- Alyaa Mahmoud "Love all, trust a few, do wrong to none"- Shakespeare [[alternative HTML version deleted]]