Hi, I have a batch of arrays loaded into a marrayRaw object called Apo. The zipped .RData file containing the object is available at http://www.gch.ulaval.ca/ltarca/shares/ApoRaw.zip I am trying a composite normalization with: library(marray) sc2DA <- maNormMain(Apo, f.loc = list(maNorm2D(),maNormLoess(x="maA",y="maM",z="maPrintTip")), a.loc=maCompNormA()) I get the following error message "Error in xy.coords(x, y) : x and y lengths differ" However the same command works fine on the swirl data set data(swirl) sc2DA <- maNormMain(swirl, f.loc = list(maNorm2D(),maNormLoess(x="maA",y="maM",z="maPrintTip")), a.loc=maCompNormA()) I suspect the NAs in the object Apo but however maNormMain is expected to take care of them, is that right? (Package: marray, Version: 1.4.9, R 1.9.0) thanks, Laurentiu Tarca

> I suspect the NAs in the object Apo but however maNormMain is expected to > take care of them, is that right? > (Package: marray, Version: 1.4.9, R 1.9.0) I can't answer your primary question, but I will point out that the current version of marray (as of yesterday's BioC 1.4 release) is 1.5.8, and updating might very well solve your problem. -J