Thank you Mike for having answered very quickly! Best, Hugo Le 23/12/2013 14:45, Michael Love a écrit : > hi Hugo, > > We are not planning at the moment to have results() generate multiple > contrasts, but I will keep it in mind. > > best, > > Mike > > > On Mon, Dec 23, 2013 at 5:10 AM, Hugo Varet <hugo.varet@pasteur.fr> <mailto:hugo.varet@pasteur.fr>> wrote: > > Dear Michael Love and list members, > > I'm used to analyze RNA-seq data with your nice DESeq2 package > (1.2.0) and I sometimes have to test complex null hypotheses using > contrasts. For one of my project, I would like using multiple > contrasts, i.e. testing for example (H0: beta1-beta2 = beta3-beta4 > = 0) against (H1: beta1-beta2 != 0 and/or beta3-beta4 != 0), where > the beta's are the regression coefficients of the models. To do > so, I would like using a numeric matrix for the contrast argument > in results(), but it only accepts a numeric vector. > > Hence, I was wondering if you planned to extend DESeq2 to the use > of multiple contrasts? > > Best regards, > > Hugo > > -- > Hugo Varet > Plate-Forme Transcriptome et Epigénome > Institut Pasteur > > _______________________________________________ > Bioconductor mailing list > Bioconductor@r-project.org <mailto:bioconductor@r-project.org> > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor > > [[alternative HTML version deleted]]