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Phinney, Brett
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@phinney-brett-6324
Last seen 8.1 years ago

Hi everyone, I have been experimenting with using EdgeR with
proteomics data (spectral counts for now). I was a little confused how
the TMM normalization works on proteomics data. I basically just read
in my spectral counting data as a data matrix
And then
normFactors <- calcNormFactors(counts)
but I'm not sure exactly how it is calculating the normalization
factors?
Any help would be greatly appreciated
Cheers
Brett
---
Brett S. Phinney, Ph D.
UC Davis Genome Center
www.proteomics.ucdavis.edu<http: www.proteomics.ucdavis.edu="">
cell = 530-771-7055
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