Dear all,

I am looking for a way to filter SNPs in a VCF File separated by a X kb distance between each others (in order to increase the independency between loci). Is the width parameter of the IRanges() function the appropriate way to go? I also considered filtering with the VariantAnnotation package but I cannot find any explicit built-in function to extract the POSITION information of each variant.

Many thanks again for your help,

Kind regards,

Rémi