Question: (Closed) UPC and Sequence file to remove GC bias
0
gravatar for sanj
4.6 years ago by
sanj20
United Kingdom
sanj20 wrote:

Hi,

 

I have been trying to use UPC_Generic_ExpressionSet function from the SCAN UPC package with Human Exon Array dataset and was stuck at a point. I want to use UPC based detection and correct for GC content but the sequence file for Affymetrix is at probe level whereas I am using alternative exon array mappings from BrainArray. Thus the expressionset contains SCAN normalised intensities at exon level. In this case do I need to supply information about sequence of each exon? If not then how should I approach this when using alternate mappings?

Thanks.

 

 

 

ADD COMMENTlink written 4.6 years ago by sanj20

Hello sanj!

Questions similar to yours can already be found at:

We have closed your question to allow us to keep similar content in the same thread.

If you disagree with this please tell us why in a reply below. We'll be happy to talk about it.

Cheers!

ADD REPLYlink written 4.6 years ago by James W. MacDonald51k
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