FourCSeq - Significant changes between condition without replicate
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@julienpontis-8490
Last seen 6.0 years ago
Switzerland

Hi,

Is there a way to compare significant changes between sample without replicate ?

Regards,

Attis

fourcseq • 598 views
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@wolfgang-huber-3550
Last seen 5 days ago
EMBL European Molecular Biology Laborat…

It depends on what you mean by 'significant'. Without replicates, you can look at the differences between the z-scores and choose a cutoff by eyeballing the data, perhaps requiring consistency across neighbouring fragments.

Have a look at the accompanying paper and the package documentation (vignette).

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