I have a box running Redhat FC2, R-2.0.1 and Bioconductor 1.5. I've installed among other packages "affy" and tried: library("affy") it went OK (first time). After, I downloaded from devel-site: http://bioconductor.org/repository/devel/package/Source/ hexbin 1.1.-4 installed it without error (R CMD INSTALL hexbin.tar.gz) , but now when I try again: library("affy") I get the following message: -------------------------------- Warning message: Incorrect permissions to edit package database, /usr/local/R-2.0.1/library/liblisting.Rda in: save.locLib(locLibList, curLib) Any ideas please?